最新刊期
卷 64 ， 期 5 ， 2025
- 摘要：GPR158， a member of class C GPCRs， has attracted much attention for its unique roles in neurotransmission and emotion regulation recently. The interaction between GPR158 and RGS7-Gβ5 complex has shown potential values in the pathological process of neuropsychiatric diseases such as depression. To better understand how GPR158 interacts with RGS 7-Gβ5， in the study， we coexpressed the GPR158-RGS 7-Gβ5 complex by using baculovirus expression system，and then purified for Cryo-EM sample preparation. During data processing， some GPR158 were found to form homotetramers and interacted with RGS7-Gβ5 unexpectedly， and a GPR158 homotetramer structure with a resolution of 0.422 nm was finally obtained. The structure shows that two pairs of GPR158 dimers are arranged side by side. Meanwhile， the structure of GPR158 tetramer， as the first one to be resolved in GPCR family， lays the foundation for subsequent structural research of GPCR oligomers.关键词：GPCR;GPR158;tetramer;Cryo-EM;structure determination295|464|0更新时间：2025-11-14
- 摘要：This study aimed to elucidate the flocculation dynamics and floc characteristics of microalgae under varying volume fractions. Using Chlorella sp. and Nitzschia palea as model species， we conducted controlled experiments in an annular flume to systematically analyze the response of algal aggregation to hydrodynamic conditions. Experimental results demonstrated that the floc size of Chlorella sp. exhibited a concentration-dependent increase， expanding from approximately 8 μm at 0.02% to 22 μm at 0.08%. In contrast， N. palea displayed an inverse trend under identical conditions， with floc size decreasing from approximately 20 μm at 0.02% to 13 μm at 0.08%. Significant alterations in particle size distribution were observed in Chlorella sp.， transitioning from dispersed particles to large aggregated flocs with increasing concentrations， while N. palea maintained limited flocculation propensity. Notably， Chlorella sp. exhibited rapid flocculation at 0.06%， forming flocs exceeding double the size observed at lower concentrations. The research findings indicate that the morphology of microalgae has a significant influence on their flocculation behavior. The spherical structure of Chlorella sp. facilitates flocculation more readily than the rhomboid structure of N. palea， furthermore， characteristics such as algal secretions may also lead to variations in flocculation efficiency. These findings provide critical insights into microalgal flocculation mechanisms and offer valuable references for understanding material transport processes in aquatic systems.关键词：microalgae;Chlorella sp.;Nitzschia palea;flocculation;particle size distribution188|137|0更新时间：2025-11-14
- 摘要：Using 5-（1-oxoisoindolin-2-yl）isophthalic acid （H2oia） and （1E，2E）-1，2-bis（1-（pyridin-4-yl）ethylidene）hydrazine （bpeh） as organic ligands， a novel coordination compound ｛［Cd（oia）（bpeh）0.5（NMP）（H2O）］n｝ was self-assembled with Cd2+ at 100 ℃ using the solvothermal method. The structure and properties of this compound were characterized through single crystal X-ray diffraction， powder X-ray diffraction， thermogravimetry， SEM， EDS and solid-state fluorescence analysis. Results revealed that the complex constitutes a 1D ladder chain structure formed by the deprotonated oia2- and the N-containing ligand bpeh that are connected to the seven-coordinated Cd2+ centers. Furthermore， selective fluorescence experiments demonstrated that this coordination compound can simultaneously detect MnO4- and Cr2O7- anions in aqueous environments.关键词：coordination polymer;crystal structure;fluorescence recognition;detection of dichromate ion;detection of permanganate ion136|150|0更新时间：2025-11-14
- 摘要：Cerium （Ce）， the most abundant rare earth element in the lanthanide series， is widely utilized in catalysis， polishing， and functional materials. However， excess Ce（IV） could induce hepatorenal toxicity， hematological disorders， and increased carcinogenic risks. Current Ce（IV） detection methods predominantly rely on expensive analytical instruments and complex sample pretreatment procedures， while conventional fluorescence analysis suffers from severe interference by the autofluorescence of Ce（III）. To address these challenges， we developed an innovative room-temperature afterglow nanoprobe （IPA@NP） using a facile one-pot hydrothermal synthesis with isophthalic acid as the sole precursor. The IPA@NP exhibits unique dual-emission afterglow characteristics， displaying two distinct peaks at 385 nm and 502 nm under 300 nm excitation， with naked-eye-visible afterglow persisting for 6 s post-UV cessation. Notably， Ce（IV） induces concentration-dependent quenching of both afterglow emissions. Leveraging this phenomenon， we established the self-calibrated ratiometric afterglow sensing platform for Ce（IV）， which offers three key advantages over conventional methods： （1）Dual-channel ratiometric detection enhances quantitative accuracy； （2）Afterglow signals eliminate interference from Ce（III） and other fluorophores； （3）"Zero-background" detection achieves ultrahigh sensitivity. Under optimized conditions， the proposed method exhibits a linear detection range of 8.00×10⁻⁶ to 1.00×10⁻⁴ mol/L with the limit of detection （LOD） as low as 1.67×10⁻⁶ mol/L （3σ/k）. The proposed assay exhibits exceptional anti-interference capability and stability， enabling accurate Ce（IV） quantification in real water samples. This work provides a promising tool for Ce（IV） analysis in real sample， opening new avenues for rare earth element detection with minimized matrix effects.关键词：room-temperature afterglow materials;Ce（IV）;isophthalic acid;ratiometric probe126|114|0更新时间：2025-11-14
- 摘要：The experimental characterization of dynamic mechanical responses under complex stress states is crucial for engineering materials. In composite loading experiments， uniaxial compression testing requires minimal interfacial friction between the specimen and the loading surface to ensure the accuracy of stress measurement， while shear/torsion loading necessitates strong interfacial constraints to effectively transmit the load. For soft materials with low elastic modulus and high poisson's ratio （such as silicone rubber and hydrogels）， this incompatibility of interfacial constraint conditions is particularly prominent， and the resulting systematic errors can reach a magnitude comparable to the intrinsic mechanical response of the material. Based on the split Hopkinson pressure bar experimental platform， this paper investigates the influence of end-boned constraints on the dynamic mechanical behavior of silicone rubber. The experimental results showed that specimens under end-bonded conditions exhibit significantly enhanced apparent stress amplitudes， with this strengthening effect intensifying as the specimen's aspect ratio increases. To effectively eliminate the measurement deviation introduced by end-bonding， three correction theories were compared. The analysis found that all three correction methods could effectively eliminate the pseudo-size effect caused by friction interference within a certain strain range and showed good correction effects. However， during large-strain stages of specimens with greater diameters， correction deviations occur across all three linear friction correction models， likely attributable to material accumulation at contact interfaces inducing significant changes in frictional conditions.关键词：soft materials;split Hopkinson pressure bar;dynamic compression;end constraint;stress correction107|410|0更新时间：2025-11-14
- 摘要：The challenge of domain generalization stems from two inherent limitations in current person re-identification benchmarks：1）significant inter-dataset domain gaps， and 2） insufficient intra-dataset diversity. While existing multi-domain joint training approaches attempt to address these issues， they often fail to fully exploit latent discriminative identity cues across datasets. To address the aforementioned limitations，our framework enhances network generalization capabilities through a dual-branch strategy： knowledge distillation employed from a large-scale pre-trained model along with mask image feature mining performed on existing multi-domain training data. Extensive experiments on popular domain generalization person ReID benchmarks demonstrate that our method can achieve superior performance. Notably， our approach achieves a 16.2% Rank-1 accuracy gain over the baseline and a 3.6% improvement over existing state-of-the-art methods under the leave-one-out protocol using Market-1501.关键词：person re-identification;domain generalizable;knowledge distillation;masked image104|126|0更新时间：2025-11-14
- 摘要：This study investigates the numerical solution efficiency and memory consumption of Poisson equation，heat conduction equation， and wave equation， using a non-overlapping domain decomposition method（DDM）.To address the large-scale and singular nature of interface problems between subdomains generated by DDM，the balanced domain decomposition（BDD）method was employed.This method integrates conjugate gradient iteration with preconditioning techniques.The parallel algorithm is based on a symmetric multiprocessing（SMP）architecture，where all processor units are equal in status and share memory. First， the implementation of DDM and BDD based on the Poisson equation is introduced. Next，the finite element discretization processes and corresponding discrete matrix forms for the three PDEs are presented.Then，by increasing the total degrees of freedom while maintaining
- 摘要：This study presents a dynamic shared parking demand allocation model based on bi-level programming， aiming to optimize the matching between parking demand and available resources. A hybrid allocation framework is developed that incorporates irregular parking resources， with branch-level virtual parking lots serving as the basic spatial units. Parking allocation is carried out through a rolling time-window optimization mechanism， and a co-evolutionary genetic algorithm embedded with a distance-priority heuristic is employed for solution search. A case simulation in a branch-level area of Chengdu demonstrates that the model effectively satisfies parking demand， reduces the hourly average volume of irregular parking by 128 vehicles， and improves the spatiotemporal utilization of physical parking resources by 9.52%. Sensitivity analysis confirms the model’s robustness and adaptability to fluctuating demand conditions， showing strong robustness and adaptability.关键词：shared parking allocation;bi-level programming;co-evolutionary genetic algorithm105|133|0更新时间：2025-11-14
- 摘要：To investigate the key factors influencing the severity of conflict between passengers and non-motor vehicles on slow-moving shared paths adjacent to bus stops， minimum forecast post-encroachment time， deceleration rate to avoid crashes， and yaw rate are used as conflict evaluation indicators are used as conflict evaluation indicators， and the conflicts are classified by severity through the K-means clustering algorithm. 19 explanatory variables were considered in terms of conflict features， passenger， non-motor vehicle and road environment. A multivariate ordinal logistic model is constructed to analyze the significant variables on the severity of conflict. The results show that the road section， road crossing behavior， the number of waiting passengers occupying the road， parking behavior， sunshade installation， the density of non-motor vehicle， the arrangement of pedestrian/non-motor vehicle segregation facilities， and illegal parking at the entrance/exit of bus stop， are the important influencing factors on the severity of the conflict.关键词：traffic safety;bus stop;slow-moving shared path;multivariate ordered Logistic model;conflict severity95|148|0更新时间：2025-11-14
- 摘要：This study conducts a systematic analysis of the stall characteristics of BWB aircraft， combining numerical simulation with flow field structure analysis to reveal their aerodynamic behavior and stall mechanisms. The detached eddy simulation method is adopted， and a delay function is introduced for the boundary layer to simulate the full aircraft flow field under different angles of attack and transonic conditions. This study finds that the lift coefficient reaches a peak of 1.943 7 at an attack angle of 35°， followed by a decline due to intensified airflow separation. In transonic flow， strong shock waves in the outer wing region induce increased wave drag and flow separation， while a significant horseshoe vortex system forms at the junction of the central fuselage and outer wing， with vorticity diffusing and dissipating along the spanwise direction. Through the analysis of surface pressure and vorticity distribution， the influence of shock wave-boundary layer interaction， three-dimensional flow separation， and vortex system evolution on the stall process is clarified， providing key theoretical basis for the layout optimization of BWB aircraft.关键词：blended wing-body;stall characteristics;detached eddy simulation;flow characteristics74|400|0更新时间：2025-11-14
- 摘要：Simulating realistic three-dimensional （3D） forest scenes is key to studying the relationship between forest ecosystem structure and biodiversity at the structural scale. Light detection and ranging （LiDAR） point cloud voxelization is widely used for 3D forest reconstruction， but it usually overestimates the leaf areas of canopies. Here we propose an improved rotational slice-based voxelization method for 3D forest reconstruction. Using two synthetic forest scenes， we compared different 3D reconstruction methods by simulating airborne laser scanning data and multi-spectral imagery based on HELIOS++ （Heidelberg LiDAR operations simulator）， VBRT （voxel-based radiative transfer）， and PBRT （physically based ray tracer）， respectively. Experimental results show that the slice-based and randomly rotated leaf models significantly improve canopy realism and produce a higher correlation with benchmark results for key metrics， such as point cloud height distribution and canopy coverage， compared with the traditional cubic voxelization. The new voxelization method proposed in this study enhances the visual effects and accuracy of simulated remote sensing data， contributing to more accurate and realistic 3D forest reconstruction and demonstrating good potential in forest radiative transfer modeling.关键词：three-dimensional forest reconstruction;light detection and ranging （LiDAR）;airborne laser scanning （ALS）;terrestrial laser scanning （TLS）;voxelization148|407|0更新时间：2025-11-14
- 摘要：FengYun-4A （FY-4A） is China’s first next-generation geostationary meteorological satellite. This study addresses two scientific questions related to the direct assimilation of radiance data from its onboard Advanced Geostationary Radiation Imager （AGRI）：1）how assimilating these observations improves the accuracy of extreme precipitation forecasts and 2）whether multi-channel joint assimilation provides better forecast performance compared to single-channel assimilation. Within the weather research and forecasting（WRF）and gridpoint statistical interpolation（GSI）framework， alternative observation operators were employed to assess the direct assimilation capability of the GSI system for FY-4A AGRI infrared radiance data under clear-sky conditions. A series of assimilation-forecast experiments were conducted to evaluate the impact of cycling assimilation on the prediction of an extreme precipitation event associated with a monsoon depression. Results indicate that experiments employing the Geostationary Operational Environmental Satellite-15 （GOES-15） IMAGER observation operator to directly assimilate four infrared channels （3.75，6.25，10.8 and 13.5 μm） from FY-4A AGRI， as well as experiments additionally incorporating the Himawari-8 Advanced Himawari Imager （AHI） observation operator for another three infrared channels （7.1， 8.55 and 12.0 μm， totaling seven channels）， produce more pronounced positive analysis increments of water vapor mixing ratio. These increments exhibit greater central intensity， broader horizontal distribution， and deeper vertical coverage over critical oceanic regions. Consequently， the assimilation significantly improves the representation of low-level warm-moist conditions in regional high-resolution numerical forecasts， markedly enhancing the predicted spatial distribution and orientation of extreme precipitation events.关键词：AGRI radiance data;extreme precipitation forecast;WRF model;GSI data assimilation system;South China67|404|0更新时间：2025-11-14
- 摘要：Investigating the trends and potential for carbon sequestration in the organic carbon storage of cultivated land topsoil can guide agricultural production management. This study focuses on Lianzhou ， integrating measured soil data with multi-dimensional geographic information to investigate. It employs a combined model algorithm and the DNDC （denitrification-decomposition）model to simulate and analyze the spatio-temporal variations in soil organic carbon density and carbon sequestration potential in the topsoil. The results indicate that the SA-LSTM-XGB combination algorithm， which integrates remote sensing and terrain factors， yields the best predictive performance， with a determination coefficient R2 of 0.646. According to the model， the soil organic carbon density of surface farmland in Lianzhou decreased from 4.73 kg/m2 in 2007 to 3.35 kg/m2 in 2019. Simulations using the DNDC model suggest that if field management practices remain unchanged， the overall organic carbon storage in the top 50 cm of cultivated land in Lianzhou will continue to decline at an annual average rate of 3.32×107 kg from 2019 to 2035. However， with improved field management practices， the soil organic carbon in the top 50 cm of cultivated land in Lianzhou could increase by between 1.48×109 and 2.52×109 kg by 2035.关键词：soil organic carbon;carbon sequestration potential;DNDC model;Lianzhou48|384|0更新时间：2025-11-14
- 摘要：Accelerating the formation of new-quality productive forces is essential for adancing Chinese-style modernization and high-quality development. This study established an evaluation index system for new quality productive forces through a systematic analysis of their fundamental principles and dimensional attributes. We employed the comprehensive index method to measure the development levels of new quality productive forces in Guangdong Province and its prefecture-level cities from 2013 to 2022. Using exploratory spatial data analysis， we revealed the spatial correlation characteristics of these development levels， and further investigated their influencing factors through spatial econometric models. The results indicate that： （1） The development level of new quality productive forces in Guangdong demonstrated a consistent upward trajectory during the study period. （2） Spatially， the province gradually formed a dichotomy pattern where medium-level and high-level cities predominantly clustered in the Pearl River Delta （PRD）， while low-level cities aggregated in eastern， western， and northern Guangdong. （3） Spatial analysis revealed a diffusion trend in the agglomeration effects， with PRD cities maintaining high-value clusters and western Guangdong cities persisting as low-value clusters. （4）The spatial Durbin model identified significantly promoted impacts from technological advancement， foreign investment， industrial structure optimization， and marketization， whereas government intervention exhibited significantly inhibitory effects. Education expenditure and financial support are statistically insignificant.关键词：new-quality productive forces;spatio-temporal evolution;spatial Durbin model（SDM）;Guangdong73|104|0更新时间：2025-11-14
- 摘要：Let
- 摘要：An evolution inequality of Sobolev type involving a nonlinear convolution term is considered. By using the nonlinear capacity method and the contradiction argument, the non-existence of the nontrivial local weak solution is proved.关键词：Sobolev type evolution inequality;nonlinear convolution term;nontrivial solution;non-existence108|106|0更新时间：2025-11-14
- 摘要：The stability of solution sets for parametric set-valued optimization problems is studied in normed vector space. Firstly， the concepts about
- 摘要：To investigate the risk of renal artery stenosis （RAS） in the development of abdominal aortic aneurysm （AAA）， we established a location-size dual variable model and systematically analyzes the mechanism of AAA enlargement at different locations on renal artery hemodynamics by CFD. The position-specific effects show that in the presence of suprarenal AAA， the area of the low-velocity recirculation zone on the caudal side of the renal artery increases， and its duration almost covers the entire cardiac cycle. This is distinctly different from the situation in healthy vessels， where the recirculation zones on the cranial and caudal sides of the renal artery appear alternately in a cardiac cycle. As the aneurysm enlarges， the wall shear stress on the caudal side of the renal artery deteriorates significantly， characterized by a decrease in time-averaged wall shear stress （TAWSS）， and increases in oscillatory shear index （OSI） and relative residence time （RRT）. This further forms a high-risk area for endothelial dysfunction， suggesting an increased risk of stenosis on the caudal side of the renal artery. There is also a size-related critical phenomenon： when the suprarenal AAA expands to 55 mm， there is a coexistence of improved macro-scale flow recirculation and intensified micro-scale wall shear stress fluctuations. Additionally， when perirenal AAA expands from 30 mm to 55 mm， the study indicates an increased risk of stenosis on the caudal side of the renal artery. In contrast， infrarenal AAA has little disturbance on the hemodynamics of the renal artery. This study provides quantitative evidence for early hemodynamic warning and decisions on intervention timing in AAA cases accompanied by RAS.关键词：abdominal aortic aneurysm;renal artery stenosis;hemodynamics;computational fluid dynamics;wall shear parameters114|96|0更新时间：2025-11-14
Research articles
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