The effects of rare earth ions Ce3+

Tb3+ on the patterns of four chicken isozymes (POD

SOD

AKP and ACP) were investigated by utilizing PAGE and IEF methods. The results indicated:(1)Under the action of Ce 3+ and Tb 3+

the variations of POD and SOD electrophoresis patterns are relatively small

while the patterns of AKP and ACP varying remarkably;(2)the effects of Ce 3+

Tb 3+ on the isozymes vary with the organs where they are extracted; the POD and SOD in the liver show a evident stability-even when the rare earth concentration reaches 1 000×10 -6 in the feed

the variations of their patterns are still quite limited; but the patterns of the same isozymes in the kidney and muscle vary markedly. The results imply isozymes are appropiate markers to monitor the biological effects of rare earth on living body.